v1-2: The fall of Babylon the great, detailed in chapters 17-18, is referred to in 14.8. It may be that, chronologically these chapters fit in there, preceding the seven bowls. Jer 51.13 describes Babylon as being by many waters.
v3-5: There is a scarlet beast, with the adulterous woman, the great city of Babylon, see v18. Here is false religion, carrying away the inhabitants of the earth, influencing them for evil. She is wealthy, and appears attractive to men, but brings abominable things. See also Ezek 28.1-19, where the prophet describes the city of Tyre in similar terms.
v6: Babylon maintained an attitude of antagonism towards the saints and martyrs of Jesus. Babylon is ‘the embodiment of all entrenched worldly resistance to God' (African Bible Commentary).
We read several times of the presence of believers on the earth; 7.1-8; 9.4; 13.7; 14.1-5, 12-13; 18.4,24; after the church is raptured, Jews are restored to Christ, and many suffer and are killed.
v7-11: The explanation of the woman and the beast. The beast dies, but is revived, and most of the inhabitants of the earth follow it, being astonished at it.
We notice here that there is interpretation of the vision, as is found also in Dan 7-12. The mind needs godly wisdom (v9) to understand these things.
v12-14: The beast has great power and widespread authority, ruling over the ten kings. Yet he is defeated by Christ Himself. However powerful and fearful are these enemies of Christ, they will all be defeated; we need not fear.
v15-18: The kingdom is divided against itself, and cannot stand. The woman, the great city with world-wide domination, will find traitors amongst her friends, and be destroyed by them.